C17 RESEARCH GRANTS

C17 Research Grant Competition Funding  

To learn more about the C17 Research Network and upcoming grant competitions, please see the Research Network Committee page.

Over $5,200,000 has been awarded to outstanding C17 research grants since 2005.  Congratulations to all of our awardees! 

Research results and publication references are posted as they become available.

 

2016 Research Grants

 Round 18 

Dr. Henrique Bittencourt of CHU Ste Justine was awarded $120,000 for his grant entitled "Third-party Human Umbilical Cord Perivascular (HUCPVC)-derived Mesenchymal Stromal Cells (MSC) to Treat Refractory or Steroid-dependent Acute Graft-versus-Host Disease after Allogeneic Hematopoietic Stem Cell Transplantation in Children, TUMS Phase I-II trial". Funded in partnership with Childhood Cancer Canada Foundation.

Dr. Jason Berman from IWK was awarded $99,930 for his grant entitled "Stromal Antigen 2 (STAG2): A novel metastatic pathway in Ewing sarcoma". Funded in partnership with the Ewings Cancer Foundation of Canada and the Childhood Cancer Canada Foundation.

 

2015 Research Grants

 Round 17 

Dr. William Foulkes of the Research Institute of the McGill University Health Center was awarded $119,890 for his research project "Towards a pan-Canadian DICER1 clinical and research network". Funded in partnership with Childhood Cancer Canada Foundation.   

Publications for Foulkes - round 17

Dr. Faisal M. Khan of the Alberta Children’s Hospital Research Institute was awarded $115,000 for his research project "Genetic Profiling of Killer Immunoglobulin-Like Receptors (KIRs) of Natural Killer Cells as Predictors of ATG-Conditioned HLA-matched Pediatric Allogeneic Hematopoietic Cell Transplantation (HCT) Outcomes".  Funded in partnership with the Kids With Cancer Society and the Childhood Cancer Canada Foundation. 

Publications for Khan - round 17

Dr. Tal Schechter of The Hospital for Sick Children was awarded $107,125 for her research project "A population-based study of long-term outcomes in survivors of allogeneic hematopoietic stem cell transplantation during childhood, adolescence or young adulthood".  Funded in partnership with the Childhood Cancer Canada Foundation. This was Dr. Schechter's second C17 grant. 

 

2014 Research Grants

Round 16

Dr. Jonathan Wasserman of the Sick Kids Research was awarded $149,518 for his research project "Genetic Characterization of Pediatric Papillary Thyroid Carcinoma". Funded in partnership with the Kids With Cancer Society and the Childhood Cancer Canada Foundation.   

Dr. Anne Klassen of McMaster University was awarded $149,554 for her research project "Development and Validation of Distress Screening Tools for use by Canadian Adolescent and Young Adult (AYA) Cancer Patients & Survivors".  Funded in partnership with the Kids With Cancer Society and the Childhood Cancer Canada Foundation.  This was Dr. Klassen's third C17 grant.  

Publications for Klassen - round 16

Dr. Adam Shlien and Dr. David Malkin of The Hospital for Sick Children were awarded $100,000 for their research project "The Transcriptional Consequences of Somatic Mutation in Ewing’s Sarcoma".  Funded in partnership with the Ewings Cancer Foundation of Canada and the Childhood Cancer Canada Foundation.

Dr. Yigal Dror of The Hospital for Sick Children was awarded $90,000 for his research project "Canadian Aplastic Anemia and Myelodysplastic Syndrome Study(CAMS)-Opening a registry and initiating the first study to apply next generation sequencing to identify genetic predispositions that affect treatment decisions in aplastic anemia".  Funded in partnership with the Aplastic Anemia & Myelodysplasia Association of Canada and the Childhood Cancer Canada Foundation.  This is Dr. Dror's fourth C17 grant. 

2013 Research Grants

Round 15

Dr. Nancy Baxter of St. Michael’s Hospital and Dr. Paul Nathan of The Hospital for Sick Children were awarded $179,676 for their research project "Initiative to Maximize Progress in Adolescent Cancer Therapy (IMPACT)".  Funded in partnership with the Kids with Cancer Society and the Childhood Cancer Canada Foundation.   

Publications for Baxter and Nathan - round 15

Dr. Sylvain Baruchel and Dr. Arif Manji of The Hospital for Sick Children were awarded $149,066 for their research project "A Phase I study of Oral Metronomic Topotecan and Pazopanib in Pediatric patients with recurrent or refractory solid tumours (TOPAZ)".  Funded in partnership with the Kids with Cancer Society and the Childhood Cancer Canada Foundation.  This is Dr. Baruchel's third C17 grant.   

Dr. Rosanna Weksberg and Dr. Armando Lorenzo of The Hospital for Sick Children were awarded $150,000 for their research project "Determination of molecular signatures that allow differentiation between unilateral and bilateral Wilms' tumours using genome-wide arrays and whole-exome sequencing".  Funded in partnership with the Childhood Cancer Canada Foundation/ St Baldricks Foundation.      

DVL (Developmental Therapeutics) Round 2

Dr. Michel Duval of Hôpital Ste. Justine was awarded $81,000 for his DVL research project "Pre-clinical models of natural killer cell-based immunotherapy to cure refractory childhood acute lymphoblastic leukemia".  Funded in partnership with the Childhood Cancer Canada Foundation.   

Publications for Duval - DVL 2 

2012 Research Grants 

Round 14

Dr. Armando Lorenzo and Dr. Abha Gupta of The Hospital for Sick Children were awarded $79,054 for their research project "Parent, provider, and survivor perspectives of investigational fertility preservation interventions for pre-pubertal boys with cancer: Exploring the factors influencing decisions and measuring preferences".  Funded in partnership with the Kids with Cancer Society, the Childhood Cancer Canada Foundation/ St Baldricks Foundation, and the Coast-to-Coast Against Cancer Foundation.

Publications for Lorenzo - round 14 

Dr. Paula James of Queen's University and Dr Margaret Rand of The Hospital for Sick Children were awarded $186,500 for their research project "Generation and Validation of the Self-PBQ (Self Administered Pediatric Bleeding Questionnaire)".  Funded in partnership with the Childhood Cancer Canada Foundation and the Coast-to-Coast Against Cancer Foundation. 

Publications for James - round 14 

Dr. Yigal Dror of The Hospital for Sick Children was awarded $200,000 for his research project "Bone marrow failure-causing alleles in Canada and genotype phenotype correlation".  Funded in partnership with the Childhood Cancer Canada Foundation/ St Baldricks Foundation, and the Coast-to-Coast Against Cancer Foundation.  This is Dr. Dror's third C17 grant.     

Publicatons for Dror - round 14 

Dr. Jason Berman of IWK Health Centre and Dr. Poul Sorensen of the University of British Columbia were awarded $100,000 for their research project "Elucidation of YB-1 as a metastasis driver through angiogenic mechanisms in Ewing family tumours using zebrafish and mouse models".  Funded in partnership with the Ewings Cancer Foundation of Canada, Childhood Cancer Canada Foundation and the Coast-to-Coast Against Cancer Foundation.    

Publications for Berman - round 14 

DVL (Developmental Therapeutics) Round 1

Dr. Richard Kim of the London Health Sciences Centre and Dr. Alexandra Zorzi of The Hospital for Sick Children were awarded $25,830 for their DVL research project "Pharmacogenetic analysis of cyclophosphamide metabolism in pediatric acute lymphoblastic leukemia patients".  Funded in partnership with the Childhood Cancer Canada Foundation/ St Baldricks Foundation and the Coast-to-Coast Against Cancer Foundation.    

Publications for Kim - DVL 1 

Dr. Sylvain Baruchel of The Hospital for Sick Children was awarded $45,000 for his DVL research project "In vivo anti-tumour and anti-metastatic activity and functional imaging of Palifosfamide in preclinical neuroblastoma models".  Funded in partnership with the Childhood Cancer Canada Foundation/ St Baldricks Foundation and the Coast-to-Coast Against Cancer Foundation.  

2011 Research Grants

Round 13  

 

Dr. Maru Barrera of The Hospital for Sick Children was awarded $197,684 for her research project "Assessing the Efficacy of a Psychosocial Intervention Program for Siblings of Children with Cancer".  Funded in partnership with the Childhood Cancer Canada Foundation/ St Baldricks Foundation, and the Coast-to-Coast Against Cancer Foundation. 

Publications for Barrera - round 13     

Dr. Donna Johnston of Children's Hospital of Eastern Ontario (CHEO) was awarded $190,926 for her research project "Phase I Dose Finding Study for Melatonin in Pediatric Oncology Patients with Relapsed Solid Tumours".  Funded in partnership with the Childhood Cancer Canada Foundation and the Coast-to-Coast Against Cancer Foundation.

Publications for Johnston - round 13   

 

Dr. Anne Klassen and Dr. Samantha Anthony of McMaster University were awarded $156,093 for their research project "What Factors do Children with Cancer and Childhood Cancer Survivors Say Are Important to Understanding their Quality of Life? A Qualitative Study".  Funded in partnership with the Kids with Cancer Society, the Childhood Cancer Canada Foundation, and the Coast-to-Coast Against Cancer Foundation.  This was Dr. Klassen's second C17 grant.  

Publications for Klassen - round 13 

  Round 12  

Dr. Lucie Lafay-Cousin of Alberta Children's Hospital was awarded $201,658 for her research project "Identification of Prognostic Factors and Therapeutic Tragets in Childhood CNS Atypical Teratoid Rhabdoid Tumors (ATRT)".  Funded in partnership with the Kids with Cancer Society, the Childhood Cancer Canada Foundation, and the Coast-to-Coast Against Cancer Foundation.

Publications for Lafay-Cousin - round 12 

DVL (Developmental Therapeutics) Round 0

Dr. Sandi Dunn of the University of British Columbia was awarded $30,000 for her DVL research project "Potential for PLK inhibitors in CNS tumours".  Funded in partnership with the Childhood Cancer Canada Foundation, and the Coast-to-Coast Against Cancer Foundation.  

Dr. Sylvain Baruchel of The Hospital for Sick Children was awarded $10,000 for his related DVL research project "Potential for PLK inhibitor in Neuroblastoma and sarcomas".  Funded in partnership with the Childhood Cancer Canada Foundation, and the Coast-to-Coast Against Cancer Foundation.  

Publications for Baruchel - DVL   

 Dr. Aru Narendran of Alberta Children’s Hospital was awarded $30,000 for his DVL research project "Potential for PLK inhibitors in leukemia".  Funded in partnership with the Childhood Cancer Canada Foundation, and the Coast-to-Coast Against Cancer Foundation. 

2010 Research Grants 

Round 11 

 

Dr. Jennifer Stinson of The Hospital for Sick Children was awarded $199,929 for her research project "Development and Testing of a Multidimensional Electronic Pain Diary for Youths with Cancer".  Funded in partnership with the Kids with Cancer Society, the Childhood Cancer Canada Foundation, and the Coast-to-Coast Against Cancer Foundation. 

Publications for Stinson - round 11 

Ms. Lee Dupuis and Dr. Tal Schechter-Finkelstein of The Hospital for Sick Children were awarded $199,840 for their research project "Pharmacological Predictors of Successful Cyclosporine Acute Graft versus Host Disease Prophylaxis in Children Undergoing Haematopoietic Stem Cell Transplant".  Funded in partnership with the Childhood Cancer Canada Foundation/St. Baldricks Foundation and the Coast-to-Coast Against Cancer Foundation. 

Publications for Dupuis and Schechter-Finkelstein - round 11 

Round 10 

Dr. Uma Athale of McMaster University was awarded $198,400 for her research project "Central Venous Line Dysfunction as a Predictor of Thromboembolism in Children with Cancer".  Funded in partnership with Childhood Cancer Canada Foundation/St.Baldricks Foundation and the Coast-to-Coast Against Cancer Foundation. 

Publications for Athale - round 10 

2009 Research Projects

 

Round 9

 

Dr. Yigal Dror of The Hospital for Sick Children was awarded $120,300 for his second C17 research project "Characterization of Myelodysplastic Syndrome Secondary to Inherited Marrow Failure Registry (CIMFR)".  Funded in partnership with both Childhood Cancer Canada and the Coast-to-Coast Against Cancer Foundation.   

Publications for Dror - round 9 

Dr. Ute Bartels of The Hospital for Sick Children was awarded $119,997 for her research project "A randomized controlled multicenter non-inferiority trial of twice daily low dose dexamethasone versus high dose dexamethasone for symptom control in children after complete or near complete (≥95%) resection of a brain tumour undergoing cranial or craniospinal radiation".  Funded in partnership with both the Childhood Cancer Canada Foundation and the Coast-to-Coast Against Cancer Foundation.      

Round 8

 

Dr. Shayna Zelcer and Dr. Danielle Cataudella of the London Health Sciences Centre were awarded $113,393 for their research project "Development of the P-SCS: The Pediatric Supportive Care Scale".  Funded in partnership with both the Childhood Cancer Canada Foundation and the Coast-to-Coast Against Cancer Foundation.

Publications for Zelcer - round 8  

Dr. Paul Steinbok of BC Children’s Hospital was awarded $117,785 for his research project "Thalamic Brain Tumours in Canada in the MRI Era".  Funded in partnership with both Childhood Cancer Canada and the Coast-to-Coast Against Cancer Foundation.  

Final Report and publications for Steinbok - round 8   

2008 Research Grants

Round 7 

 

Dr. Evan Shereck of BC Children's Hospital was awarded $111,930 for his research project "ADP Signaling Defect as a Potential Cause for Aplastic Anemia".  Funded in partnership with both the Aplastic Anemia Association of Canada and the Childhood Cancer Canada Foundation.  This study is now being completed by Dr. Kirk Schultz of BC Children's Hospital.

Ms. Lesley Mitchell of the Stollery Children's Hospital was awarded $120,000 for her research project "Relationship of Prothrombotic Markers to Thrombosis in Survivors of Childhood Cancer".  Funded in partnership with the Childhood Cancer Canada Foundation.  

Publications for Mitchell - round 7   

Dr. David Malkin of The Hospital for Sick Children was awarded $59,484 for his research project "The Estrogen Receptor Pathway as a Therapeutic Target in Rhabdomyosarcoma".  Funded in partnership with the Childhood Cancer Canada Foundation - Sandra Sharpe Rhabdomyosarcoma Fund.   

Round 6 

 

Dr. Jacqueline Halton of the Children's Hospital of Eastern Ontario (CHEO) was awarded $133,591 for her research project "Osteonecrosis in children with acute lymphoblastic leukemia".  Funded in partnership with both the Kids with Cancer Society and the Childhood Cancer Canada Foundation.    

2007 Research Grants

Round 5

 

Dr. Juliette Hukin of BC Children’s Hospital was awarded $120,000 for her research project "Evaluation of Biomarkers in Relation to Recurrence Rate in Childhood Ependymoma".  Funded in partnership with both the Kids with Cancer Society and Childhood Cancer Canada Foundation.

Hukin Final Report and Publications for Hukin - round 5 

Dr. Andrea Downie of the Children’s Hospital in London, Dr. Sharon Guger of The Hospital For Sick Children, and Dr. Isabelle Montour-Proulx of the Children’s Hospital of Eastern Ontario (CHEO) were awarded $111,740 for their research project "The Role of Intrathecal Methotrexate, Triple Intrathecal Therapy, and High Dose Intravenous Methotrexate in Predicting Neurocognitive Outcome in Survivors of Childhood Leukemia".  The funding partner of this study was the Childhood Cancer Canada Foundation. 

Publications for Downie - round 5 

Round 4 

Dr. Don Mabbott of The Hospital for Sick Children was awarded $95,000 for his research project "Neuro-imaging of white matter and neuro-cognitive outcome following cranial radiation for pediatric brain tumors".  Funded in partnership with both the Kids with Cancer Society and Childhood Cancer Canada Foundation.

 Publications for Mabbott - round 4  

Dr. Anne Klassen of McMaster University was awarded $92,715 for her research project "Immigrant Families’ Experiences of Care for their Child with Cancer".  Funded in partnership with the Childhood Cancer Canada Foundation.  

Publications for Klassen - round 4

2006 Research Grants

 

Round 2 

 

Dr. Michel Duval of Hôpital Sainte-Justine was awarded $50,000 for his research project "The Effect of Maintaining a Higher Hemoglobin Level on Neutropenia Duration after Bone Marrow Transplantation in Children: A Pan-Canadian Multicenter Randomized Controlled Clinical Trial".  The funding partner for this study was the Childhood Cancer Canada Foundation.  

Publications for Duval - round 2

Round 3

Dr. Rod Rassekh of BC Children’s Hospital was awarded $72,548 for his research project" Genotype-Specific Approaches to Therapy in Children with Cancer (GATC Cancer)".  Funded in partnership with the Childhood Cancer Canada Foundation.   

Publications for Rassekh - round 3

2005 Research Grants 

 

Round 1 

 

Dr. Lillian Sung of The Hospital for Sick Children, was awarded $17,000 for her research project "Prospective Cohort Study of Genetic Variation and Risk of Infection in Canadian Children with Acute Myeloid Leukemia".  The funding partner for this study was the Childhood Cancer Canada Foundation.  

Publications for Sung - round 1

Dr. Yigal Dror of The Hospital for Sick Children was awarded $83,000 for his research project "Defining the Clinical Phenotype of Inherited Marrow Failure Syndromes and the Risk Factors for Severe Hematological Complications and Cancer by the Canadian Inherited Marrow Failure Registry (CIMFR)".   The funding partner for this study was the Childhood Cancer Canada Foundation. 

Publications for Dror - round 1